ADAPT: Active Awards

National Institute of Health, R01MH094650                                                                              Project Title: Frontal-Subcortical Development, Movement Abnormalities, and Risk for Psychosis                                                                                                                                    Principal Investigator: Vijay A. Mittal, Ph.D.                                                                                        Project Period: 06/01/2011-02/29/2018                                                                                         Total Direct Cost: $1,820,544                                                                                                            Co-Is: Randal Ross, M.D., Marie Banich Ph.D., Mark Brown Ph.D.                                                     Goal: Investigate spontaneous movement abnormalities as a potential biomarker for white matter and grey matter development components of frontal-subcortical circuits, in adolescents at high-risk for psychosis.

National Institute of Mental Health Translational Research for the Development of Novel Interventions for Mental Disorders: R21/R33 Award, MH103231                                               Project Title: Exercise and markers of medial temporal health in youth at ultra high-risk for psychosis.                                                                                                                                              Principal Investigators: Vijay Mittal, Ph.D., Angela Bryan                                                                  Project Period: 07/2014-6/2019                                                                                                        Total Direct Costs: $850,000                                                                                                             Co-I: Randal Ross, M.D.                                                                                                                   Goal: To test feasibility and to design a pilot controlled trial investigation of cardiovascular exercise and medial temporal neurogenesis and cognitive/functioning remediation in youth at high-risk for schizophrenia.

National Institute of Mental HealthR21 MH 110374                                                               Project Title: Neural Habituation in Ultra High-Risk Youth                                                       Principal Investigators: Vijay Mittal, Ph.D.                                                                                   Project Period: 04/2017-3/2019                                                                                                        Total Direct Costs: $275,000                                                                                                               Co-Is: Tim Curran, Ph.D., Holly Earls, Ph.D.                                                                                     Goal: Evaluate timing of affective recognition deficits in youth at clinical high-risk for psychosis.

Brain Behavior Research Foundation Independent Investigator Award. (NARSAD)                  Project Title: Brain stimulation targeting cerebellar-cortical circuits and verbal working memory in psychosis                                                                                                                          PI: Vijay Mittal, Ph.D.                                                                                                                         Project Period: 9/15/2017-8/2019                                                                                                        Total Direct Costs: $99,000                                                                                                            Co-I: Jessica Bernard                                                                                                                     Goal: A functional magnetic resonance imaging (fMRI), double-blind cross over study designed to determine if targeted cerebellar brain stimulation will normalize brain activation and behavioral task performance in individuals with schizophrenia performing a verbal working memory task.

Buffett Institute for Global Study, Scholars in Israel Collaboration                                              P.Is Matthew Goldrick, Vijay Mittal, Emily Cibelli, Joseph Keshet, Yossi Adi, Jennifer Cole         Date: 06/2017-5/2017                                                                                                                       Total Award: $25,000                                                                                                                         A Multidisciplinary Approach to Predicting Schizophrenia                                                            Goal: To use machine learning to evaluate movement markers of risk for psychosis.

Northwestern Weinberg College Research and Innovation Grant (W Award)                               Project Title: Using motor control disruptions in speech to predict risk for psychotic disorders Principle Investigator: Emily Cibelli, Matthew Goldrick (Department of Linguistics); Vijay Mittal   Direct Costs: $35,000                                                                                                                  Project Period: 9/2017-8/2018                                                                                                           Goal: To develop software for analyzing speech patterns indicating increased risk for psychosis.                                                   

Current Mentored Awards

Canadian Institutes of Health Research (CIHR), Doctoral Foreign Study Award                Project Title: Cortical Midline Structures and Self-Reflection in youth at ultra-high risk for psychosis                                                                                                                                        Principle Investigator:Raffles Cowan                                                                                           Dates: 9/2017-8/2020                                                                                                                    Mentors: Dan McAdams, Vijay Mittal

Past Awards

Northwestern Data Science Initiative Award                                                                                   Project Title: Automated analysis of vocal characteristics for early detection of schizophrenia      Project Period: 06/2016-05/2017                                                                                                Principle Investigator: Emily Cibelli, Ph.D.  Matthew Goldrick, Ph.D. Vijay Mittal, Ph.D.                Total Direct Costs: $30,000                                                                                                              Goal: To Evaluate early motor dysfunction in speech signifying risk for psychosis.

Intermountain Neuroimaging Consortium (INC) Pilot Award                                                 Project Title: Default Mode Network Hyperconnectivity Across theSchizophrenia Spectrum     PI: Vijay Mittal and Jessica Turner                                                                                                Project Period: 2012-2013                                                                                                               Goal: To examine potential hyperconnectivity patterns across the psychosis spectrum

National Institute of Health (NIH) Clinical Research Loan Repayment Award (2009-2012) NIH- L30 MH087258:01-02                                                                                                          Project Title: Dyskinetic Movements and Glucocorticoids in Adolescents At-Risk for Psychosis Principal Investigator: Vijay A. Mittal, Ph.D.                                                                                  Goal: This project is designed to investigate the roles between stress reactivity, reciprocal dopamine activation, and potentially consequent neuromotor dysfunction

National Institute of Mental Health (NIMH) National Research Service Award (NRSA)/Training NIMH NRSA T32 MH14584-33                                                                     Principal Investigator: Keith Nuechterlein, Ph.D.                                                                  University of California Los Angeles, Department of Psychology                                             Role: Postdoctoral Fellow

Past Mentored Awards

Brain Behavior Research Foundation: NARSAD Young Investigator Award                                Project Title: Cerebello Prefrontal Involvement in Error Processing and Rule Learning in Youth at Ultra High-Risk for Psychosis                                                                                                           Principle Investigator Jessica Bernard, Ph.D.                                                                                   Project Period: 1/1/2015-1/1/2017                                                                                                          Total Direct Costs: $60,000                                                                                                                 Mentor: Vijay Mittal, Ph.D. Co Mentor: Banich

National Research Service Award (NRSA), 1F31MH100821-01A1                                                   Project Title: The neural basis of social cognition in adolescence                                                Project Period: 10/01/2013-9/30/2016                                                                                                 Principle Investigator Andrea Pelletier, M.A.                                                                            Mentor: Vijay Mittal, Ph.D. Co-Mentors: Tor Wager, Jessica Turner

National Research Service Award (NRSA) 1F32MH102898-01                                                     Project Title: Cerebellar contributions to disease course in youth at high-risk of psychosis        Project Period: 10/01/2013-9/30/2015                                                                                                  Principle Investigator: Jessica Bernard, Ph.D.                                                                                   Mentor: Vijay Mittal, Ph.D. Co-Mentor: Marie Banich, Jessica Turner